4,4'-Dimethoxytriyl chloridehe nucleoside ikaika a me ka hui nucleotide e pale ana a e hoopau ana.
ʻōlelo like:DMT-Cl
Helu CAS:40615-36-9
Waiwai
ʻO ke kimekema
Kaumaha Molekala
Ka Mahana Waihona
Lae hehee
Maemae
ʻO waho
C21H19ClO2
338.82 g/mol
2~8 ℃
120-125 ℃
≥98%
ʻulaʻula Crystalline
Ma ke ʻano koʻikoʻi o nā kaulahao nucleic acid, hana nui nā nucleosides a me nā nucleotides i ka lawe ʻana i ka ʻike genetic.Eia nō naʻe, ma muli o kā lākou hana kemika a me ka hoʻohaʻahaʻa maʻalahi, pono nā nucleosides a me nā nucleotides i nā reagents kūikawā e pale iā lākou i ka wā synthesis.ʻO DMTCl4 'Dimethoxytrityl (DMTCl) kahi hui maikaʻi loa e pale a hoʻopau i ka mea i hoʻololi i ka pale o nā nucleosides a me nā nucleotides i ka wā synthesis.
ʻO DMTCl kahi mea hoʻomalu hydroxyl e hoʻopili koho me nā pūʻulu hydroxyl o nā nucleosides a me nā nucleotides i ka wā synthesis e hana i kahi pūʻulu pale no ka manawa e pale ai i nā nucleosides a me nā nucleotides mai ka hana ʻana me nā kemika ʻē aʻe.Hoʻopau maʻalahi kēia pūʻulu pale no ka manawa ma hope o ka synthesis, e waiho ana i nā nucleosides maʻemaʻe a i ʻole nucleotides.
Ma muli o kāna hana maikaʻi a me ke koho,DMTClhoʻohana nui ʻia ma ke ʻano he hui pale a hoʻopau i ka mea hana i ka synthesis o DNA, RNA a me nā ʻakika nucleic ʻē aʻe.He mea pono loa ia no ka oligonucleotide synthesis kahi e koi ʻia ai ka mana pololei ma ke kūlana nucleotide a me ke kaʻina.
Ma waho aʻe o ka hana ʻana ma ke ʻano he mea pale a me ka eliminator, ʻo DMTCl kahi mea pale hydroxyl ikaika o nā nucleosides a me nā nucleotides.Mālama ia i nā pūʻulu hydroxyl o nā nucleosides a me nā nucleotides mai ka oxidation, hoʻemi, a me nā hopena ʻē aʻe e hiki ke hōʻino iā lākou i ka wā synthesis.
I ka hōʻuluʻulu manaʻo,DMTCl4 4' dimethoxytriylHe mea hana koʻikoʻi ia no ka hoʻohui ʻana i nā nucleosides a me nā nucleotides.ʻO kāna hana maikaʻi loa, koho a me ka versatility e lilo ia i hui kūpono e pale a hoʻopau i ka mea hana a me ka hydroxyl protecting agent no DNA, RNA a me nā synthesis nucleic acid.Inā makemake ʻoe i ka palekana kiʻekiʻe a hilinaʻi o nā nucleosides a me nā nucleotides i ka wā synthesis, mai nānā ʻoe ma mua o DMTCl.
Ka manawa hoʻouna: Jun-08-2023